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Stressors such as physical exertion may lead to mitochondrial structural damage and functional impairment, resulting in reduced ATP synthesis, an increase in ROS production, and the accumulation of metabolic byproducts, such as lactate

doi: 10.1007/BF00014969 20 GaffneyT.FriedrichL.VernooijB.NegrottoD.NyeG.UknesS.et al