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Tracking body fat percentage, lean muscle mass, and key metabolic or hormonal markers helps guide decisions over time and provides insights beyond the scale

The most common side effects include gastrointestinal issues such as nausea, diarrhea, and vomiting

A 2024 paper in Science used optogenetics and human fMRI to identify GLP-1 receptor neurons in the dorsomedial hypothalamus as the substrate for the preingestive satiation these drugs produce the sense of fullness before you finish eating

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In the same GLP1R gene region, another variant was found to be associated with the side effects of nausea and vomiting

Chew thoroughly: Digestion begins in the mouth