Acknowledgements Financial support is acknowledged from: the Ministero dell'Istruzione, dell'Universit e della Ricerca (Progetti di Rilevante Interesse Nazionale PRIN 2017), the Universit degli Studi di Salerno (FARB 2017), the SPRING cluster (REBIOCHEM research project CTN01_00063_49393), the Regione Campania for the FT-ICR mass spectrometer facility (POR CAMPANIA FESR 2007/2013 O.O.2.1, CUP B46D14002660009), the Farma-BioNet (CUP B25C13000230007) and the Centro di Tecnologie Integrate per la Salute for the 600 MHz NMR facility (CITIS, project PONa3_00138)
Ageing: Over time, the skins natural ability to regulate melanin weakens, leading to age spots
Aging and changes in substance metabolism associated with obesity may aggravate ferroptosis
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154 Natural product erianin increases the accumulation of ROS and Fe 2+ in KRAS G13D colon cancer cells, causing cellular lipid peroxidation and mitochondrial morphological changes, thereby inhibiting their migration and invasion
Apart from its antioxidant activities, glutathione has two other major functions: It is important for the body's own detoxification and improves the performance of the immune system
