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To unlock wider and more equitable access to novel obesity treatments, however, positive cardiovascular outcomes data will be absolutely critical to demonstrate substantial cost-savings for health systems from medication-assisted weight loss by avoiding downstream complications from obesity-related comorbidities

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The GLP-1 receptor system GLP-1 stands for glucagon-like peptide-1

But last month, GLP-1s were introduced in pill form, a major innovation

All randomised patients completed the 12-week duration of the trial and drug compliance was full

However, real-world data and clinical experience when switching between GLP-1 medicines suggest that many patients tolerate the transition well, with side effects generally limited to those commonly seen with GLP-1 treatments, such as nausea, constipation, diarrhoea, reflux, or reduced appetite