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As clinical pharmacology data of oral semaglutide were characterised by high within-subject variability, potential changes to the disposition model obtained by including oral data were judged to be less credible, as the changes could be the result of changed estimation procedures and difficulties with the estimation

If youre looking at semaglutide as a life-changing, but temporary, intervention, consider that you cant rely solely on the drug if you want to come off after reaching your goal weight

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