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In some formulations, paracetamol is combined with the opioid codeine, sometimes referred to as co-codamol (BAN)

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Glob Med Genet 10:205220

Dosage considerations include: Starting dose: Begin with lower doses (e.g., 100 mg daily) to assess tolerance Divided dosing: Larger doses may be split into two or three doses throughout the day Duration: Effects may take 4 to 12 weeks to become apparent in studies Quality: Choose supplements from reputable manufacturers complying with UK/EU standards Do not exceed: Follow manufacturer's directions unless advised otherwise by a healthcare professional It is important to recognise when medical advice should be sought