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Together, these findings support a role for ABHD11 in controlling CD8 + T cell differentiation, with implications for 2-OG metabolism and oxygen tensions in contributing to the phenotypic differences between T cell states (Fig

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In both regions, NSCs also show a hierarchy of division: glial-like type B cells divide relatively infrequently to give rise to rapidly dividing type C transit-amplifying cells, which in turn generate immature type A neuroblasts that mature into fully differentiated neurons (Riquelme et al., 2008) (Figure 1)