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Glycoengineering has been successfully used to increase exposure and pharmacodynamics of darbepoetin, a hyperglycosylated analogue of erythropoietin 35 and our glycosylated GLP-1 analogue peptide fusion variant Ab#2_GLP1 W25N V27S showed indeed in vivo stability improvement (Fig

Dias et al., 2018

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Gut microbiota-derived short chain fatty acids operate as mediators of the gutbrain axis targeting age-related neurodegenerative disorders: a narrative review