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Heerspink HJL, Stefnsson BV, Correa-Rotter R, Chertow GM, Greene T, Hou F-F, Mann JFE, McMurray JJV, Lindberg M, Rossing P, Sjstrm CD, Toto RD, Langkilde A-M, Wheeler DC

Sloth B, Davidsen L, Holst JJ, Flint A, Astrup A

Sustainable results require addressing the root causes of weight gain alongside medication, not relying on medication alone

150,152,153 Activation of the GLP-1R can enhance insulin secretion, reduce glucagon secretion, delay gastric emptying, 154 and suppress appetite

Once you have used the pen for your first dose, it can stay in the refrigerator or at room temperature (up to 86F) for up to 56 days

When GLP 1s reduce inflammation, appetite becomes more stable