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It consists of a four-base pair deletion (c.401_404delTTCT, first reported as c.397_400delTTCT) in the MPTb domain, which causes a frameshift and premature termination of the protein (Phe134CysfsTer8) [73]
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Never discontinue any medication without consulting your healthcare provider
They amplify the insulin sensitivity of peripheral tissues while reducing glucose synthesis in the liver, but they can also result in fluid retention, potentially worsening heart failure
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