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Additionally, other medications commonly used in patients with metabolic disorders may contribute to sexual dysfunction, including certain antihypertensives (especially thiazide diuretics and beta-blockers), antidepressants (particularly SSRIs), 5-alpha-reductase inhibitors, and opioid analgesics

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In the brain, APAP has been shown to produce selective inhibition the COX pathway, while this inhibition by APAP is absent in peripheral tissues such as the stomach (17

Reich K, Hartl C, Gambichler T, Zschocke I

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