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Most service members complete weight loss during garrison time and discontinue before deployment, with weight management maintained through diet and training

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Higher doses reached that plateau later in the trial. In a 112-week step-down trial, participants maintained 21.9% loss on the top dose, 16.6% after stepping down to 5 mg, and 9.9% on placebo

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Literature on this topic is too large to summarise comprehensively, but it suffices to say that GLP1R agonists are capable of increasing the activity of neurons that promote satiety, while simultaneously decreasing the activity of neurons that promote hunger