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If GI symptoms are severe, the solution is slower dose titration (extending intervals between increases from 4 weeks to 68 weeks), eating smaller meals with lower fat content, and potentially adding ginger or vitamin B6 which have anti-nausea effects through different mechanisms

Weeks 48: Increase intensity , integrate plyometric precursors if appropriate

By activating GLP-1 receptors in the brain, Semaglutide influences the hypothalamus which the part of the brain involved in regulating hunger and satiety

Common side effects include nausea, constipation, bloating, and fatigue, especially when starting

When combined with dietary and lifestyle changes, it offers sustainable results