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Deletion of the gene encoding ABCA1, responsible for lipidating ApoE in the CNS, resulted in an increase in A deposition (Wahrle et al., 2005) Conversely, overexpression of ABCA1 resulted in a decrease in A deposition (Wahrle et al., 2008) in amyloid mouse models, suggesting that increasing ApoE lipidation can reduce A pathology

La causa ms comn de infarto al miocardio o accidente cerebrovascular es la ruptura de las placas aterosclerticas en las paredes arteriales que causan la formacin de cogulos sanguneos (trombognesis)

Employer-based health insurance coverage for these prescription drugs currently lags behind this evidence: only one fourth of large employers offer coverage of GLP-1s for weight loss to their employees

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