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It functions by binding to several melanocortin receptors, including MC1R, MC3R, and MC4R

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HO pretreatment further enhanced the structure and function of damaged ovaries, reducing granulosa cell apoptosis and restoring sex hormone levels (increased E2 levels and decreased FSH levels) by improving the migration ability and survival rate of hUC-MSCs [118]

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After incubated for the time points described in the figure legends at room temperature, the reactions were arrested by adding the proteoliposome solution to 200 l ice-cold wash buffer and aspirating it through 0.22-m membrane filters (Millipore, MSGVN2210) under vacuum

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