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Its mechanism involves appetite regulation, increased energy utilization, and enhanced insulin sensitivity, demonstrating greater efficacy than current monotherapies (Tschp et al., 2023)

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Innate immune activation in obesity

DPP-4 inhibitors are small molecular-weight drugs that inhibit 90% of DPP-4 activity and are orally administered on a once-daily (OD) basis [vildagliptin twice daily (BID)] 11 , 12

It is not approved or reviewed by the U.S