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8 Also in Japan, in 2007, patients with the incurable neurodegenerative disease ALS (Lou Gehrigs disease) received daily injections with 25 mg methylcobalamin for 4 weeks, followed by daily injections of 50 mg intravenously, followed by 50 mg a week

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And on top of all this, some research suggests that lower estrogen levels may also promote fibrosis (a buildup of thick, stiff, scar-like tissue) within the shoulder joint