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doi: 10.1016/j.isci.2019.05.030

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GLP-1 medications mimic a natural gut hormone that lowers blood sugar, slows digestion and helps people feel full and lose weight, but where semaglutide drugs like Wegovy and Saxenda only mimic GLP-1 receptors, tirzepatide medications, better known as Zepbound for weight loss and Mounjaro for treatment of Type 2 diabetes, mimic two receptors

The glomerulus, a cluster of blood vessels inside the nephrons, function as the actual filter