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[DOI] [PubMed] [Google Scholar] 204.Boss O, Hagen T, Lowell BB

Lemaire I

Most experts recommend limiting use to twelve weeks followed by an equal rest period

This results in a healthier complexion and reduced skin irritation

One of the most promising strategies to overcome this multi-drug resistance, MRP1-mediated CS, relies on the ability of certain ligands of MRP1 to induce a massive MRP1-dependent GSH efflux, that depletes the cells of their anti-oxidant defense, leading to their selective cell death 15