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2 3 The proposed mechanisms include promotion of angiogenesis (new blood-vessel formation), effects on the nitric-oxide system, and stimulation of fibroblast outgrowth and cell migration through signaling pathways such as FAK-paxillin

Moreover, while intrahippocampal BDNF infusion facilitates neurogenesis, 21 there is no direct evidence that a local reduction in the BDNF protein actually impairs adult hippocampal neurogenesis in vivo

Although the drop in hepatic or renal GSH is the most toxicologically relevant interaction (see also below), plasma GSH, free cysteine (Pujos-Guillot et al., 2012)

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In Iranian patients, mean serum Cu and zinc levels were also significantly lower in patients with lower segmental and non-segmental vitiligo than in the control group [104]