The most commonly recommended protocol is 2 mg daily via subcutaneous injection for 10 to 12 weeks, followed by a 4 to 6 week rest period
Marso SP, Baeres FMM, Bain SC, Goldman B, Husain M, Nauck MA, et al
This suggests that although there is a reduction in lean mass with semaglutide treatment, there is an improvement in muscle function
From missed or delayed periods , to weeks of heavy bleeding with clots , to the return of cycles after years away , users on Reddit are raising questions about how this powerful GLP-1 medication is interacting with their hormones
Frontiers in Physiology, 9 .
Continuous administration does not seem to provide additional benefit and may actually diminish the compound's effectiveness over time