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Molecules administered by IN can reach the CSF and brain parenchyma within minutes of dosing, offering a rapid therapeutic onset, which might be beneficial in acute settings, including acute brain injuries or stroke

However, the literature is not uniformsome reports show androgen-associated functional impairment rather than simple hyperactivationunderscoring that androgen effects depend on dose, timing, and the systemic inflammatory milieu [36]

17% for placebo

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Prostaglandins Leukot Essent Fatty Acids 73:379384 Ming X, Johnson WG, Stenroos ES, Mars A, Lambert GH, Buyske S (2010) Genetic variant of glutathione peroxidase 1 in autism

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