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In addition, inter-population variation in genetic background, particularly in oxidative stressresponse genes and xenobiotic-metabolizing enzymes, may modify individual susceptibility to pollution-related reproductive toxicity

Methods In Vitro Cell Culture Use of human erythrocytes was approved by the La Trobe University Research Ethics Committee (ethics number HEC17013) and an Australian Red Cross Blood Service Agreement (Deed 19-05VIC-01)

This information indicates they may have a genetic mutation associated with the MTHFR gene

10.1038/s41586-021-03539-7 14 MishimaE.NakamuraT.ZhengJ.ZhangW.MouraoA