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A post hoc analysis in Japan indicated that the combination of SGLT2i and GLP-1RA was superior to monotherapy in improving liver function parameters (ALT, AST), hepatic steatosis index (HSI), and fibrosis index (FIB-4), suggesting complementary mechanisms between the two

Both compounded semaglutide and brand-name Wegovy have appropriate use cases

Data availability Data used in these analyses are available on Open Science Framework ([ (https:/osf.io/r2whq)), with age provided in bands to preserve participant anonymity

Remove the cap from the pen and attach a fresh needle each time

If you reconstitute with sterile water instead, bacterial contamination risk increases with every needle puncture, and the effective usage window drops from 28 days to 710 days maximum

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