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But it's also possible that GLP-1s can have a direct impact on the brain, Jari Tiihonen, MD, PhD, professor in the Department of Clinical Neuroscience at Karolinska Institutet, tells SELF

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Imagine youre a GLP-1 user, down 20 pounds and feeling fabulous, but your arms are starting to look like spaghetti noodles because protein intake is a struggle