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Another analysis that included 10 years of data from 1,158 study subjects found blood levels of persistent endocrine disruptors known as per- and polyfluoroalkyl substances (PFASs) were also generally associated with lower risk of fibroids (Wise 2025)

15 Conclusion Definitive conclusions regarding natural compounds remain challenging due to variations in formulation, routes of administration, and the limited size of clinical studies