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While most of these commenters supported the standardization of the lookback period, many commenters expressed concern with the 12-month timeframe

Of note, a feed-forward loop may occur whereby IL-1 itself triggers further mtDNA release, sustaining inflammation (44, 45)

Mol Biochem Parasitol 61 , 155158, doi: 0166-6851(93)90169-X (1993)

Extended Usage: Ideal for multiple doses, thus minimizing waste

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