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Obesity-associated adipose tissue secretes proinflammatory cytokines and adipokinessuch as leptin and TNF- which negatively affect upper airway neuromuscular control and respiratory regulation (50)

GLP-1 receptor agonists are not typically associated with drug-induced liver injury and generally do not cause liver damage

[9] [10] Semaglutide is FDA-approved for specific indications, and prescribing decisions should align with these approved uses rather than treating insulin resistance as an isolated condition

By activating GLP-1 receptors in the brain, Semaglutide reduces feelings of hunger and increases sensations of fullness

FDA-approved versions of these medications have demonstrated impressive results in clinical studies, but tirzepatide may produce slightly greater weight loss due to its dual-hormone activation

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