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Inflammatory changes at the injection site

In the limited human research conducted, DSIP was generally described as well tolerated, with few acute adverse events reported at the doses studied

The NHS notes pain and itching at the injection site as common and self-limiting

The direct renin inhibitor aliskiren was shown to have antiarrhythmic potential by reestablishing normal ventricular conduction velocities due to restoration of connexin 43 expression in a DCM mouse model [109]

For example, people who maintain a vegetarian or vegan diet, people with absorption disorders, and those taking prescription meds like Metformin, Proton Pump Inhibitors (PPIs), and H2 blockers like Pepcid are often at greater risk