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Clinical practice guidelines suggest several scenarios where dose modification may be appropriate: Persistent gastrointestinal symptoms lasting beyond the first week of a new dose level may warrant extending that dose phase by an additional 2-4 weeks before further escalation

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Jensen et al.) Pharmacokinetics: Half-life, dosing frequency, receptor residence time (Gydesen et al

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Eligibility requires meeting specific BMI and clinical criteria, and beneficiaries already receiving GLP-1 drugs through Part D are excluded