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Three patients dropped out, one each owing to fatigue, elevated blood pressure, and rash

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Accessed May 2026

Injectable medications that are similar to semaglutide (Ozempic, Wegovy) include: Oral weight loss medication options include: Qsymia (phentermine/topiramate) Adipex (phentermine) Contrave (naltrexone/bupropion) Alli or Xenical (orlistat) Each medication has its own benefits, side effects, and safety considerations

In addition, DPP-4 modulates multiple substrates such as GLP-1, BNP, substance P, and neuropeptide Y (NPY), leading to potential extra-pancreatic effects, particularly the promotion of sodium excretion in urine (186)

Researchers use several benchmarks to determine whether a medication qualifies as a potential longevity drug, or gerotherapeutic, Barzilai explained