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30 A 505(b)(2) sponsor who can patent a more efficient or greener manufacturing process gains a significant cost advantage that functions as a secondary moat after the primary patents expire

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however, continuity of care may vary because appointments are not always with the same provider

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In healthy women, sham-feeding with quinine sulfate (10 mg) was reported to slow the emptying of subsequently ingested electrolyte soup, when compared to sham-feeding with a pleasant strawberry flavoring or control (no sham-feeding) (67)