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In mice pretreated with buthionine sulfoxime to inhibit GSH synthesis and induce a deficient state, oral administration of GSH resulted in statistically significant increases in GSH concentrations in kidney, heart, lung, brain, small intestine, and skin, but not in the liver

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In the pig data, plasma IGF-1, IGFBP-3, and growth hormone were all reduced by LR3 infusion (Tomas et al., 1997)