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Retatrutide Is a First-in-Its-Class Medication Retatrutide is a triple agonist medication, meaning it works on three different hormone receptors in the body: GLP-1, GIP, and glucagon leading some experts to call it a triple-G drug

Essex MJ, Shirtcliff EA, Burk LR, Ruttle PL, Klein MH, Slattery MJ, et al

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showed similar effects of a 4-week semaglutide treatment in a HFD-induced NAFLD mouse model on food intake, body weight, and insulin resistance, as well as on hepatic steatosis and inflammation

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