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The Endocrine Society recommends stopping the current GLP-1 agonist, allowing a brief washout period (typically one to two half-lives of the discontinued drug), and then beginning the new agent at its lowest dose with standard titration [11]
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Studies suggest that it may operate on the pituitary gland in a mode analogous to GHRH, potentially stimulating growth hormone production
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Chen, Y., Xia, Q., Zeng, Y., Zhang, Y
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