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Retatrutide is one of the most actively studied compounds in the metabolic and obesity research literature, following published Phase 2 clinical trial data showing substantial reductions in body weight in human study populations

[DOI] [PMC free article] [PubMed] [Google Scholar] Richard JE, Farkas I, Anesten F, Anderberg RH, Dickson SL, Gribble FM, Reimann F, Jansson J-O, Liposits Z, Skibicka KP, 2014

Loren Pickart in 1973 [2]

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Similar cAMP-mediated mechanisms may occur in GLP-1 receptive neurons, but more research is needed Figure 1