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The strong effect it has on average weight loss means retatrutide could be good for people who have not got their weight loss goals from other treatments

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Its first registrational Phase 3 obesity trial has confirmed weight loss outcomes that approach those previously achievable only through bariatric surgery, with meaningful cardiometabolic improvements alongside

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Evidence for this action has been demonstrated in mice (Fridolf et al., 1991), rats (de Heer et al., 2008), dogs (Freyse et al., 1997), and humans in vivo (Hare et al., 2009), as well as in intact isolated mouse islets (De Marinis et al., 2010)