Nausea typically improves within 8 to 12 weeks at a given dose, but constipation rates remain relatively stable across the treatment period because the medication continues to slow gut motility for as long as you take it
After MBS, especially after SG and RYGB, GLP-1 and peptide YY (PYY) levels increase, ghrelin levels decrease, and the peak rise (at 1530 min) in GLP-1 levels after mixed meal test or oral glucose tolerance test (OGTT) is higher than before BMS [12, 13]
The ability to slow down the beginning and end of an injection
Perspectives in GLP-1 research: new targets, new receptors
Gradual dose escalation as used in the clinical trials appeared to help reduce the burden of these side effects
Prescribing & titration is anticipated to lead with 46.0% share in 2026