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Your husband needs a thorough workup

Various causes, including exogenous and endogenous stress factors, an imbalance between prooxidants and antioxidants, disruption of antioxidant pathways, and gene polymorphisms, lead to the overproduction of reactive oxygen species

Perluigi M, di Domenico F, Butterfield DA (2015) mTOR signaling in aging and neurodegeneration: at the crossroad between metabolism dysfunction and impairment of autophagy

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AOD-9604 can be administered via subcutaneous injection or orally, depending on the formulation available

Oxidation can alter a proteins physiochemical characteristics (e.g., folding and subunit association) and lead to aggregation or fragmentation