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The meta-analysis calculated a weighted mean difference across all 28 studies, and found that on average , pomegranate supplementation produced a body weight reduction of 1.97 kg, corresponding to a 0.48 point drop in BMI

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At 12 mg, the trajectory suggests sustained loss well beyond the point where tirzepatide users at 15 mg have already plateaued

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Companies like Eli Lilly and Novo Nordisk are leading the development of oral alternatives designed to match the efficacy of injectables while improving convenience and adherence