flow trial semaglutide nejm Oral and Cardiovascular Outcomes in Patients with Type 2 Diabetes Semaglutide in patients with overweight

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A nasal spray must penetrate nasal mucosa, possibly deal with mucociliary clearance, and may have somewhat reduced bioavailability

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We look forward to seeing further results at CTAD, as this may suggest a path forward for semaglutide as part of a combination therapy approach

For those who prefer no needles , oral GLP-1 options are now FDA-approved

The design was clean: 102 adults with obesity, all on tirzepatide, randomized so that half also received apitegromab and half got a placebo infusion