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Determinants of GH resistance in malnutrition

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The mitochondria in the immune cells become swollen, their internal structures (cristae) break down, and they lose the ability to produce adequate ATP

As fast metabolizers receiving ER-Tac also showed a decline in eGFR and increase of acute rejection rates similar to IR-Tac (159), patients with side effects were indication-based switched from IR- to LCP-Tac