Weight loss from microdosing is likely modest and short-term, highly variable, and not guaranteedand there is still the problem of long-term maintenance if new habits are not adopted and the drug is discontinued, Zimmermann says
Headaches Headaches are reported by approximately 10% to 15% of GLP-1 users, typically in the first few weeks
The researchers also observed that 532 participants with BMI 35 at week 0, who had tolerated their assigned dose of medication, were then escalated to the maximum tolerated dose (9mg or 12mg) for a further 24 weeks
Therefore, the results from the FAERS database should be interpreted with caution as they can overestimate adverse events due to reporting bias and do not establish causality
Crucially, the pill requires no restrictions around timing or food and water intake
GLP-1RA, which was originally developed for patients with T2DM and is known for its rapid weight loss effects in obese patients, has attracted a lot of attention recently