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Graphical abstract was created by BioRender ( Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest
The key differences are in selectivity how much they activate other pathways beyond GH release
In vitro studies employing purified GLP-1/Fc indicate that the fusion protein is functional and elevates cAMP levels in insulin-secreting INS-1 cells
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Protein intake often increases on GLP-1 therapy to preserve muscle during weight loss, but excessive protein without adequate fiber can worsen constipation
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