Moreover, intellectual property issues, exclusivity rights, and high brand loyalty among customers toward branded drugs may hamper the adoption of biosimilars in some areas
Topiramate is now contraindicated for migraine prophylaxis in pregnancy and in women of childbearing potential unless a Pregnancy Prevention Programme (PPP) is followed
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Response to treatment: Symptoms, side effects, and recovery progress should be monitored during use
The reported age-related decline from comparatively high plasma levels in young adulthood to markedly lower levels by later middle age became the rationale for asking whether restoring GHK systemically could restore some of the repair competence that appears to fade with that decline
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