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In the landmark study of Glutathione and its use in Parkinson's, 600mg of Glutathione was given twice daily for 30 days in nine patients with early, untreated Parkinson's disease

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Of interest, patients with metabolic diseases, such as obesity and type 2 diabetes 35 have been reported to have a reduction of bacterial riboflavin synthesis genes in their gut microbiome, suggesting that microbially-produced riboflavin could play a role in these diseases, although the causal association remains to be established

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Key actives include Vitamin C (L-Ascorbic Acid or stable derivatives like Sodium Ascorbyl Phosphate) for antioxidant protection and inhibiting melanin synthesis