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The MR-PRESSO method was also used to evaluate the pleiotropy and to correct the estimates by eliminating outliers ( Our research strengths are as follows: first, while randomized controlled trials are widely accepted in causal studies, they are expensive, difficult to conduct, and may have confounding biases that limit their results

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He answered directly: "From the research I did previous to my exposure to the substance, the drug has been around since the late 80s in the form of Melanotan-1

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