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A reduction in CYPOR protein levels prevented NFT-dependent accumulation of Nrf2 protein and partially attenuated the NFT-dependent increase in glutathione levels

doi: 10.1002/(SICI)1097-4547(19960801)45:3 3.0.CO;2-A 78 FungG.ShiJ.DengH.HouJ.WangC.HongA.et al

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targeted the IP3 receptor (IP3R) channels and induced the downstream pro-apoptotic Ca 2+ -signaling pathway via synthesizing a peptide named Bcl-2 IP3 receptor disrupter-2 (BIRD-2) mimicking the structure of the BH4 domain of Bcl-2