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Consider starting with 30-unit syringes for the first eight weeks of escalation (0.25mg and 0.5mg doses), then switching to 100-unit syringes when doses increase beyond what the smaller syringes can accommodate

Compounded versions are prescribed under similar guidelines, though individual practitioners may vary

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Not all patients benefit equally

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The presence of B12 deficiency itself may indicate an underlying digestive disorder that requires specific investigation and management