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Amlodipine reduces blood pressure and headache frequency in cocaine-dependent outpatients

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doi: 10.1038/S41467-024-49724-W 227 DOliveira AlbanusRZhangXZhaoZTaylorHJTangXHanYet al

This innovative approach has been shown to enhance the absorption and subsequent bioavailability of a variety of supplemental nutrients, such as vitamin D3, iron, and magnesium, suggesting that it could similarly improve the efficacy of oral B12 supplementation (2529)

The compound is classified as an amylin receptor agonist with demonstrated activity at calcitonin receptor (CTR) and receptor activity-modifying protein (RAMP) complexes, particularly CTR/RAMP1, CTR/RAMP2, and CTR/RAMP3 heterodimers